CHEN 3701 Lecture Notes - Lecture 22: Opata Language
21 Oct 2015
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Process conceptual reason if have too much protein, all will be singly bound and there will be no room for double binding. Process by which a drug is input, distributed, metabolized, and eliminated from the body and its compartments (the effect of the body on the drug, how does mass transfer and metabolism impact the drug) Pharmacodynamics - opposite of pharmakokinetics; the effect of a drug on the body. Aim: describe the concentration of a substance (e. g. drug) in certain locations as a function of time. Input: many routes - enteral: introduced via a gastrointestinal (gi) trap (oral pill, sublingual (under tongue), or rectal) parenteral: other; intramuscular, subcutaneous, inhalation, transdermal patch. Various rates: bolus (single, rapid introduction) steady infusion. 2nd, we have slow decay alpha = distribution phase beta = elimination phase digoxin: small molecule antibody: large molecule digoxin antibody alpha. 240 h these times come from half times ln(2)/alpha and ln(2)/beta.
