CHEN 3701 Lecture Notes - Lecture 26: Central Dogma Of Molecular Biology, Tachykinin Receptor 1, Dna Replication
26 Oct 2015
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Last lecture, defined kon and koff in terms of k=/- and k1/-1. Rxn speed must match rate at which a diffuses to b. We have n molecules of b in close proximity. We are overcounting b molecules so we need to normalize rate constant. Having n in denominator makes rate constant deminish b/c even though lot of possiblilities, individual probabilities for each receptor are lessened usually k+ term is more dominant, but if rxn gets higher, then more effect. Set y axxix = 1/2 and olve for n1/2. We aim to produce proteins for thir functions. We aim to engineer proteins to perform these functions more efficiently. -> use cells as micron-scale factories to produce proteins. Before cell divides, it needs to copy all its dna to provide the information. Copy gene of interest (for genetic engneering) --> recombinant dna. 1 and 2 are different in how they are done but general process can be summarized below.
