KIN 3385 Lecture Notes - Lecture 1: Apoptosis, Calcitriol, Antigen

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2 Sep 2016
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Bio systems create order and maintain by finding free energy (atp) Exergonic you get more energy than necessary (net) Binding of substrate to an enzyme"s activate site has chem. Specificity, affinity, competition, and saturation when binding to protein. Metabolic function and atp production occur even without change in substrate (food) Process of increasing structure or synthesis using the pairs. Phosphorylation & de-phosphorylation is a key mechanism of regulation of metabolism. Kinases & phosphates form enzymatic loop, provides link of regulation of metabolism and level of atp. 2 atps input -> 4 atps output = 2 atps net & 2nadhs. Each time around produces 3 nadh, 1 fadh2, 1 gtp (atp) Nad & fad transport electrons/hs to electron transport chain on mitochondrial membrane. Nad &fad are coenzymes (vitamin b3 & b2) Lactic acid produced by anaerobic respiration to liver. Each 2 carbon acetyl coa off, 1 nadh & fadh2 made. Amine group forms to keto acid and ammonia.

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