PHPR 3813 Study Guide - Retrograde Amnesia, Seizure Threshold, Methohexital

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Background: originally thought that seizures helped treat/cure mental illness. The procedure: ect = relatively safe procedure, includes: Fractures & dislocations common injuries from ect. Large doses resulted in great cognitive impairment. Moa: generally unknown thought to have following effects: Reduce bf to frontal lobes (where depression propagates) Indications: depression; catatonia; tx-resistant bipolar, ocd, schizophrenia, epilepsy; depression assoc w/ organic dz; urgent needs. Should first give patient adequate trial of antidepressant medications (inc: trial of several drug classes and augmentation) Pt should have sx requiring immediate tx (i. e. psychiatric sx during preg and catatonia, especially malignant catatonia) Ect should be used as a tx bump to get patients to a spot where an add will work to tx their depression. 70-80% efficacy w/ catatonia being esp responsive (ect considered effective in. Short acting iv anesthetic to induce unconsciousness (common: methohexital, barbituates) Brief electrical currents sent thru electrodes causing generalized seizures. Seizure must lasy ~30s-60s (@120s, benzo admin to stop seizure)

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