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PHPR 3823 Study Guide - Final Guide: Tazobactam, Nafcillin, Cefepime

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vmturner96
7 Mar 2022
School
Lipscomb University
Department
PHPR - Pharmacy Practice
Course
PHPR 3823
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Document Summary

Duration 4-6 weeks iv abx: neonates vancomycin + cefepime, children cefazolin/ nafcillin vancomycin, adults (vertebral) cefazolin/ nafcillin vancomycin, ivda/ dm foot osteo/ post trauma/surgery vancomycin + anti-pseudomonal (zosyn/ carbapenem/ cefepime) Always 2-6 weeks of iv abx + rifampin po: 300 to 450 mg q12h. Rifampin po + po abx for 3 mos (tha) or 6 mos (tka) Pathogen specific: mssa nafcillin/ cefazolin/ cetriazone. Vancomycin/ linezolid/ daptomycin: mrsa vancomycin. Pathogen specific regimen: mssa nafcillin/ cefazolin, mrsa vancomycin. Empiric abx therapy: young adult ceftriaxone + vancomycin, low gonococcal suspicion vancomycin, high gonococcal suspicion - ceftriaxone, ivda vancomycin + anti-pseudomonal. Gonococcal arthritis: doc : ceftriaxone 1 g iv/im daily + 1 gram. Nongonococcal arthritis: gpc vancomycin, gnc ceftriaxone. Inpatient iv empiric antibiotics antipseudomonal b-lactam monotherapy: cefepime, ceftazidime, zosyn, meropenem, imipenem/cilastatin. Low risk outpatient oral treatment: augmentin + fq (levo/ cipro, clindamycin + fq (levo/cipro, levofloxacin/ moxifloxacin. Vancomycin: + culture/ documented pneumonia, mrsa/ pcn/ceph resistant pneumococci, cellulitis/ cather-related infxn, severe mucositis.

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In a disc diffusion assay for bacteria A, the inhibition diameter for penicillin is 2 cm while inhibition diameter for vancomycin is 0.5 cm. Which antibiotic is likely to be more effective in killing bacteria A?

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