MEDICINE Study Guide - Final Guide: Aplastic Anemia, Hypogonadism, Pancytopenia

• School: Kerala University of Health Sciences - KUHS
• Department: Psychology
• Course: MEDICINE

Document Summary

Aplastic anemia is a bone marrow failure syndrome. It is characterized by peripheral pancytopenia and general lack of bone marrow activity. It may affect not only the red blood cells but also the white cells and platelets, resulting in a pancytopenia. The clinical manifestations of the disease vary according to the type of cell chiefly affected. It is common to recognize two chief forms of aplastic anemia, primary and secondary. Disease of unknown etiology which occurs most frequently in young adults, develops rapidly and usually terminates fatally. A disease known as fanconi"s syndrome consists of congenital, and sometimes familial, aplastic anemia associated with a variety of other congenital defects including bone abnormalities, microcephaly, hypogenitalism and a generalized olive-brown pigmentation of the skin. Secondary aplastic anemia, is of known etiology, occurs at any age and presents a better prognosis, particularly if the cause is removed. Exposure of the patient to various drugs or chemical substances.