NFS 511 Study Guide - Midterm Guide: Calcium Hydroxide, Calcium Phosphate, Osteolysis
7 Feb 2023
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1: human bones grow until about age 25, ossification. The process of replacing other tissues with bone: calcification. The process of depositing calcium salts: occurs during bone ossification and in other tissues, ossification. Intramembranous ossification: bone remodeling, homeostasis, bone building (osteoblasts) and bone recycling (osteoclasts) attempt to maintain balance. If deposition is greater than removal, bones get stronger. If removal is faster than replacement, bones get weather: this process is called remodeling, sequence of remodeling, origination, after damage, osteocytes signal to surface cells to form a lining of cells where the remodeling process can take place. Factors secreted (facilitate removal of damaged bone: parathyroid hormones, il-1, il-6, calcitriol, tumor necrosis factor. Factors inhibited: estrogen, helps bone mineralization, inhibits bone resorption, il-6 is needed to stimulate bone resorption, estrogen blocks osteoblasts from secreting il-6, is estrogen beneficial for bone strength, yes!
