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1. Antibiotic resistance is a serious threat to human health. What role do beta-lactamases have in increasing bacterial resistance to drugs such as penicillin? In the future, do you feel we will be able to “solve” the antibiotic resistance problem?

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Jean Keeling
Jean KeelingLv2
28 Sep 2019
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Related questions

Utilize at least 1 credible source to support the arguments presented in your post.


Based on your knowledge of the evolution of TB resistance, assuming that the duration of antibiotic treatment impacts the distribution of cells as explored in 1b (above), and assuming that TB cells previously exposed to an antibiotic can begin dividing again when they are no longer exposed to the antibiotic (e.g., if they infect a new individual not on antibiotics), rank the long-term public health threat of the following individuals. We will define "public health threat" according to the mean antibiotic resistance of the TB cell population in the individual, with individuals with a high mean antibiotic resistance being defined as a high public threat. Put a 1 next to the individual who would be the greatest public health threat to others, a 2 next to the individual representing the next-greatest threat, a 3 next to the individual who would present the third-greatest threat, and a 4 next to the individual who would be the least public health threat to others.

_____ An infected person prior to taking antibiotics.

_____ An infected person who took antibiotics for 4 day and then stopped.

_____ An infected person who took antibiotics for 6 days and then stopped.

_____ An infected person who took antibiotics for 10 days and then stopped.

For many years, antibiotics have been effectively used to treatbacterial disease; and pesticides have been used to protect ouragricultural crops from many kinds of pests, including insects,worms (nematodes), fungi, or agricultural weeds, for example.



A growing concern for treating bacterial diseases or pest outbreaksis the evolution of antibiotic or pesticide resistance by bacterialor pest populations. Resistance means that a particular antibioticis no longer effective in treating a disease, or that a particularpesticide will no longer prevent crop damage. This resistance canbe viewed as evolution of a new trait at the population level,which is resistance to an antibiotic or to a pesticide. In thisassignment, you will explore specific examples of antibiotic orpesticide resistance.



Assignment details:



After reading materials about evolution and about antibiotic andpesticide resistance in the text, the Course Materials, the AIUOnline Library and / or the Internet, answer the following.



1.Select and describe one example of antibiotic resistance orpesticide resistance. Be specific in your choice.

◦Describe the background for your choice of resistance. Includedetails about the disease or pest and the established controlstrategies. How have we used antibiotics (to treat a particulardisease), or pesticides (to protect from a pest); and how has thischanged?

2.Explain how the resistant trait evolved based on principles ofnatural selection and evolution of a trait at the populationlevel.

3.For your specific example, what are the consequences ofresistance in terms of human health or crop loss / damage?

4.What steps can be taken to prevent or slow down the evolution ofantibiotic or pesticide resistance? Do you think we will succeed indoing so? Why or why not?

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