Question

Need help! Consider the following mutations and, for each,explain whether you expect it to be: a) potentially promotingcancer, or b) dominant or recessive.

i) A mutation that destroys the active site of an enzymenecessary to promote cell cycle

ii) A very premature STOP codon in a gene encoding a proteininvolved in the excision-repair mechanism

iii) A point mutation that renders constitutively active one ofthe signaling proteins in the Ras pathway

iv) A null mutation in a gene encoding an apoptotic(apoptosis-promoting) protein.