BIOCHEM 3H03 Study Guide - Final Guide: Syndrome Of Inappropriate Antidiuretic Hormone Secretion, Osmol Gap, Hypervolemia

• School: McMaster University
• Department: Biochemistry
• Course: BIOCHEM 3H03
• Professor: Stephen Hill

Document Summary

Spend all the energy without making atp (make heat fever) Inhibiis krebs cycle can"t get energy or stuf to feed into etc. Fever and vomiing water loss and dehydraion, perfusion is not as good, can"t carry oxygen to issues, contributes to metabolic acidosis. To compensate for respiratory alkalosis try to excrete bicard and excrete hydrogen (don"t really want to do that makes the metabolic acidosis worse) Seing threshold low to make sure we don"t miss anyone include more false posiives. Seing the threshold high to eliminate false posiives may miss people who actually have the disease, increase the number of false negaives. Case review elderly man admited to ed, confused. This guy"s urine is more dilute than plasma he is saving water. Siadh secreing adh when he doesn"t need it. Low sodium should be saving sodium via aldosterone secreion. Aldosterone secrecion simulated by blood volume (renen-angiotensin-aldosterone system) *memorize anion gap, osmolar gap, how to calculate them.