PCB-3134 Study Guide - Final Guide: Rna Polymerase Iii, Iron Response Element, Kozak Consensus Sequence
Document Summary
*regulation of gene expression occurs at all steps of process. *dna replication involves dna- directed dna pol but transcription involves dna-directed rna pol. Coding strand sequence always given when describing promoter sequences etc. *promoter sequences are upstream of gene and transcription factors bind here. For pol i and iii, due to sequence on either template or new rna. *3" polya tail: protects rna from nucleases and help bind ribosomes and needed for export to cytoplasm. *5" splice site, 3" splice site, and branch point sequence. *can have alternative 5" or 3; splice sites which give diff. mrna now. *mutually exclusive exons: have one intron in btwn but never appear together in same mature mrna transcript. *in rrna, intros are called spacers and splicing called cleavage b/c no rejoining back together. *trna: 5" end is shorter, 3" end is where acc is and where aac is and a 3" oh for aa c-terminus to bind.
