MIC 323 Midterm: Exam II 2014
Document Summary
The main conclusion of this paper was that, compared to present-day strains of yersinia pestis, the strains that were killing people during the black death were . Short answer: answer any 5 of the 6 questions listed below. Answers must be kept completely within the boxes provided. Variant carriers variant non-carriers odds ratio (95% ci) 1000 controls: contrast the trigger" and zipper" bacterial invasion strategies employed by salmonella and listeria, respectively. Listeria uses the zipper mechanism to enter a target cell. Essentially the internalin a and b proteins that reside on the surface of the pathogen bind the e-cadherin and met receptor, respectively. The inla is necessary and sufficient for entry. It utilized the zipper mechanism because the receptors bind and this triggers an endocytosis signal and the pathogen gets brought into the cell: the pathogen is taking advantage of a usual cellular process.