NURSING 2LA2 Chapter Notes - Chapter 22: Coronary Artery Disease, Hypercholesterolemia, Atherosclerosis

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Fibrous plaques commonly become evident in americans third decade. Major risk of atherosclerosis is hypercholesterolemia, which can be modified. Other risk factors can t be changes ( age, family history of chd, male) Not all atherothrombotic vascular disease can be explained by genetic and environmental risk factors: other factors can be associated with an risk for development of atherosclerosis including c-reactive protein, serum homocysteine, serum lipoprotein, and infectious agents. If the level remains markedly elevated, an alternative source of systemic inflammation should be considered. Homocysteine is derived from the metabolism of dietary methionine, an amino acid that is abundant in animal protein. However, supplementation of the above vitamins to plasma homocysteine levels is recommended for prevention of cvd. The lesions associated with atherosclerosis are of three types - fatty streak, fibrous atheromatous plaque, and complicated lesion. Increase until 20, then remain stable: damage to the endothelium is an early marker that can later become atherosclerotic.

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