NURS 2004 Chapter Notes - Chapter 8: Insulin Lispro, Prediabetes, Protamine
28 Jan 2017
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Document Summary
Symptoms result from inadequate insulin to meet body needs or resistance to actions of insulin. The primary sign of diabetes is sustained hyperglycemia (impaired glucose uptake by cells from increased glucose production. ) Hyperglycemia quickly leads to polyuria, polydipsia, ketonuria, and weight-loss. Over time, hyperglycemia can lead to heart disease, renal failure, blindness, neuropathy, Regulation of blood sugar levels is call glycemic control. Diabetes is the leading endocrine disorder, and the seventh leading cause of death. Many people live with pre-diabetes- at risk for developing diabetes. Developing diabetes is largely genetic. (factor that can"t be modified) Beta cells (responsible for insulin synthesis and release in the bloodstream) Loss/destruction of pancreatic beta cells (caused by autoimmune response-body attacks it"s own beta cells) The trigger for the immune response is not entirely known. Hyperinsulnemia- when sugar levels appear normal early in diagnosis. Reduced early in the disease and completely absent later. Insulin replacement is mandatory, along with strict dietary control.
