BIOL 1051H Chapter Notes - Chapter 22: Pulmonary Pleurae, Bronchiole, Pleural Cavity

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14 May 2018
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The Respiratory System
The respiratory system encompasses three main functions; ventilation, gas exchange
and O2 utilization. Ventilation is the movement of air in and out of the lungs for gas exchange
with blood. This is also called external respiration because of the connection with the external
environment of the body. Internal respiration is the gas exchange between the blood and the
tissue. Internal respiration also is concerned with the O2 utilization by the tissues, or cellular
respiration. Gas exchange itself takes place via diffusion of gasses across the plasma
membranes of cells.
The respiratory tract can be divided into the conducting system and the respiratory
system. The conducting system consists of those airways that serve as a conduit to move air.
Most of the respiratory tract is actually the conducting system. The conducting system can be
divided further into the upper respiratory system (nose through larynx) and the lower respiratory
system (below the larynx). You can also think of the conducting system as dead space. This
area is filled with air that must be moved in and out of the respiratory tract but does not
contribute to gas exchange. You can increase the amount of dead space by breathing through a
snorkel.
The respiratory system is that part that serves as a gas exchange area. Only the
smallest respiratory bronchioles and the alveoli are areas of gas exchange. The gas exchange
areas are the alveoli. These areas are comprised of very thin sacs. Alveolar type 1 cells
(squamous alveolar cells) are thinly stretched epithelial cells that make up 95% of the surface
area of the lung. There are also alveolar type 2 cells (which are actually more plentiful than type
1 cells but cover much less area. The type 2 cells produce surfactant, which will be discussed
more later. Also found in the alveoli are macrophages which clean up debris and help fight
infection.
The thoracic cavity is protected by the ribcage and separated from the abdomen by the
diaphragm. The lungs themselves are not anchored to the inside of the ribcage but rather move
with the ribcage due to suction between the visceral pleura (membrane on the outer surface of
the lung) and the parietal pleura (membrane covering the inner surface of the ribcage. There is
a very small amount of fluid in the space between the visceral and parietal pleura (the
intrapleural space), about 2 tablespoons of pleural fluid which lubricate the visceral and parietal
pleura as they slip across each other. The intrapleural space is considered a potential space
because in reality there is very little space there. However, if an injury occurs which allows blood
or air into that space it can become clear how much potential space is actually there.
The lungs do not have the ability to expand on their own. They rely on the suction
between the lungs and body wall and the movement of the diaphragm to increase the size of the
thoracic cavity thus lowering pressure inside the thoracic cavity and drawing air into the lungs.
Expiration is mostly accomplished by the elastic recoil of the lungs.
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Document Summary

The respiratory system encompasses three main functions; ventilation, gas exchange and o2 utilization. Ventilation is the movement of air in and out of the lungs for gas exchange with blood. This is also called external respiration because of the connection with the external environment of the body. Internal respiration is the gas exchange between the blood and the tissue. Internal respiration also is concerned with the o2 utilization by the tissues, or cellular respiration. Gas exchange itself takes place via diffusion of gasses across the plasma membranes of cells. The respiratory tract can be divided into the conducting system and the respiratory system. The conducting system consists of those airways that serve as a conduit to move air. Most of the respiratory tract is actually the conducting system. The conducting system can be divided further into the upper respiratory system (nose through larynx) and the lower respiratory system (below the larynx).

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