PSYC62H3 Chapter Notes - Chapter 9: Succinic Semialdehyde, Date Rape Drug, Prodrug
Document Summary
In the body, ghb is a metabolite of gaba: the metabolic process begins when the enzyme gaba transaminase converts. Gaba to its metabolite succinic semi-aldehyde: succinic semialdehyde reductase transforms succinic semialdehyde to ghb, certain substances serve as prodrugs for ghb. Its primary prodrugs consist of the chemical gbl and another subssatnce named. Pharmacological actions of ghb: ghb accumulates within vesicles used for storing gaba, given that gaba facilitates ghb synthesis and that the same vesicles store both. Gaba and ghb, many gaba neurons likely release both gaba and ghb: only one type of ghb receptor, research suggests there might be a second type, g-coupled protein receptor. In awake participants, ghb produced slow wave bursts characteristic of delta and theta waves. Inhalants: rapid absorption and elimination: three common approaches to inhaling solvents are called, sniffing. Involves directly inhaling vapors emitted from a small container or a soaked cloth: huffing. Inhalants: pharmacological effects and interference with oxygen intake.
