BIOL 2020 Chapter Notes - Chapter 5: Log-Normal Distribution, Glibenclamide, Multimodal Distribution
20 Apr 2020
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Particle size distributions: type of distribution, symmetrical (bell, positive skewed, negative skewed, bimodal distribution, distribution curves, frequency vs diameter, cumulative frequency vs diameter, distribution functions, normal distribution. Used for symmetrical distributions: log-normal distribution. Dg called geometric mean diameter instead of true mean diameter. Dg=d50% means that not a normal peak. Where 50% of particles are on one side: data analysis. Undersize: percentage of cates that are equal or small than 15 cm (relative to 15cm) Oversize: percent of cates that are larger than 15 cm. Frequency oversize is % of number of particles w/diameter = or larger than given diameter. For frequency undersize, we start from smallest end and move to largest; for oversize we move from largest particle size. When probablitly increases when particle size increases means its undersize. The glyburide of particle size properties detailed herin produces appropriate glyburide bioavailability in humans. Lecture 4 particle size distribution, shape and density.
