01:119:115 Chapter Notes - Chapter 17: Edward Tatum, George Beadle, Messenger Rna
28 Mar 2016
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From gene to protein: beadle and tatum: one gene one enzyme hypothesis. Wild type: live on minimal medium (few nutrients) Bombarded with x-rays geneic changes mutaion unable to produce paricular enzymes nutriional mutants. Relaionship between genes and enzyme one gene one enzyme hypothesis: each gene dictates producion of a speciic enzyme. Now know that not all proteins are enzymes one gene one protein (actually polypepide: flow of geneic informaion. Central dogma of molecular biology unidirecional low of geneic informaion. Transcripion: info in dna used to synthesisze messenger rna (mrna) Translaion ribosome uses info from mrna to synthesize a polypepide: ribosomes are the sites of translaion. Transcripion and translaion occur in all organisms prok and euk see ig 17. 3. In prokaryote translaion begin before transcripion has inished. In eukaryote nuclear envelope + rna processing: rna composiion and types. Rna = ribonucleic acid nucleic acid as is dna. Uracil (u) pyrimidine subsitutes for thymine u = a.
