NURS3403 Lecture : chapter 10 Mechanisms of Infectious Disease
Document Summary
Protein particles able to transmit infection by self-propagation. Crutchfield-jakob disease, multiple system atrophy, and kuru in humans. Human transmission from eating infected meat or receiving an infected transplant organ or cornea. Consist of a protein coat surrounding a nucleic acid core of dna or rna. Host-dependent use the host cell s metabolic machinery to replicate. May remain dormant in host cell for long periods. Normal host cells can be transformed into malignant cells (oncognesis). Gram-positive organisms: stained purple by a primary basic dye (usually crystal violet), wall: peptidoglycan. Gram-negative organisms: not stained by primary dye, but counterstain red by a second dye (safranin) Combines characteristics of both viral and bacterial pathogens to produce disease in humans. Bacterial characteristics: peptidoglycan cell wall, reproduce asexually, and contain both rna and dna. Chlamydiaceae receive nutrition from energy metabolism (i. e. , atp). Infect and cause diseases in other animals which can then be transmitted to humans.
