BIOL2117 Lecture Notes - Lecture 3: Symbiosis, Pyruvic Acid, Organelle
Document Summary
Outer membrane porins allows passive diffusion of molecules of up to ~3kda (ie. most substrates and products of mitochondrial metabolism, bigger than atp or pyruvate) It will change conformation when it binds to atp inside the mitochondria, will transport it out. Won"t go back to first confirmation immediately after releasee of atp, will wait for. Adp to bind and transport it into the cell, then will be the same as first conformation. Distribution of mpc and aac across the 3 domains of life. Can"t just go to one daughter cell - anything from mitochondria-less daughter cell won"t have one. Contraction of ftsz causes bacteria to pinch in 2, causing division event. Still open area of study dynamin-related protein 1 (drp1) is involved in mitochondria division, or is at least at the site. Dynamins form polymer that bind to membranes in helical arrangement. Gtp- hydrolysis (energy) causes in helical morphology - leads to membrane fission.
