EHR522 Lecture Notes - Lecture 10: Prediabetes, Adipose Tissue, Dyslipidemia
Document Summary
Week 10 exercise testing for metabolic clients. Effect of inactivity: chronic physical inactivity = adaption by body, low-level chronic inflammation (often reflected in elevated esr or crp, reduced insulin sensitivity, fa delivery / intracellular lipid accumulation, reduced mitochondrial efficiency and number. Decreased ability of muscle to produce atp/fatigue. Reduction in peak oxygen uptake during exercise (v02peak reduced) 150 minutes of moderate intensity exercise (brisk walking) results in a significant (58-69%) of t2dm incidence in patients with pre-diabetes. The finish diabetes prevention study; u. s diabetes prevention program; da qing study (china); Japanese diabetes prevention program: patients who have pre-diabetes, physical activity can. The time of progression from pre-diabetes to full diabetes. Overall effects of exercise: decreased cardiac risk. 2-4-fold decrease in the risk of cvd. High insulin levels of t2d improved: weight loss. Contributes to an energy deficit and weight loss. Decreased mortality: other associated benefits/normal individuals. Co-morbidities such as hypertension, hypercholesterolaemia and/or cvd.
