BIOM20001 Lecture Notes - Lecture 20: Post-Translational Modification, Repressor, Galactose
Document Summary
Transcriptional regulation: can control transcription at initiation or elongation phase. Post transcriptional regulation: can regulate by taking advantage of mrna stability (e. g. we could degrade it) Post translational regulation: can also regulate protein (e. g. post translational modification, take advantage of stability) Constitutive gene expression: when a gene is transcribed (expressed) at a relatively constant level under all conditions. For genes whose product is required continually (core or housekeeping gene). e. g. in all conditions (a,b,c) gene is always expressed. Regulated gene expression: when a gene is transcribed (expressed) only under certain cellular or environmental conditions. For genes whose product is only required under certain conditions or time. e. g. gene only expressed at condition c. Negative: this form of control results in the decrease (also called down regulation) or turning off of gene transcription. Positive: this form of control results in the increase (up regulation) or turning on of gene transcription. This is a site where rna pol binds to.
