BIOM20002 Lecture Notes - Lecture 57: Gas Exchange, Cardiac Output, Cellular Respiration

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15 Sep 2018
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Gas exchange getting o2 into the lungs. O2 from atmosphere gets to alveoli via breathing (lung mechanics), is transferred to blood, then circulates for the bodies metabolic needs. Nitrogen makes up the majority of partial pressure. Changes in atmospheric pressure at sea level are minor. The summit of mt everest is at 8850 metres above sea level - atmospheric pressure is. This proportion does not vary with altitude. po2 on summit of everest is 250*0. 21=53mmhg - does not represent po2 of inspired air on the summit of everest. Air on everest is very dry, but our mucosal membranes are moist, and humidify inspired air. Water vapour pressure is constant regardless of altitude. Water vapour pressure in fully humified air at body temperature is 47mmhg. As this does(cid:374)"t (cid:448)ar(cid:455), the effe(cid:272)ts of (cid:448)apour pressure (cid:271)e(cid:272)o(cid:373)e (cid:373)ore pro(cid:374)ou(cid:374)(cid:272)ed (cid:449)ith i(cid:374)(cid:272)reasi(cid:374)g altitude po2 inspired air on everest is (250-47)*0. 21=43mmhg. If paco2 were 40mmhg (as per sea level), pao2=-5mmhg.

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