PHYS20008 Lecture Notes - Lecture 13: Vagus Nerve, Muscarinic Acetylcholine Receptor, Blood Vessel

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Lecture 13
- Autonomic nervous system regulates all of internal environment
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- Sympathetic: fight or flight response, active when you are active, doesn’t activate
everything it touches
- Parasympathetic: active during rest, doesn’t inhibit everything it touches
- ANS: Mold internal function to task at hand; running away → ramp up heart rate and
increase blood flow to skeletal muscles, dilate pupils, open up airways, inhibit
gastrointestinal function; rerouting energy to areas of body that energy is needed at
the time (ramp up blood flow to specific organs that are going to be more active, shut
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down blood flow to organs that aren’t, increase neuronal activity of organs that need
it more, decrease neuronal activity of organs that don’t need it)
- Neuronal activity: feeding into smooth muscle, viscera is regulated by smooth
muscle
- Sympathetic nervous system: mostly out of spinal cord, neurons come down from
brain → sympathetic preganglionic neurons
- Parasympathetic nervous system: nerves out from brainstem directly to organs,
except organs of lower viscera (bladder, reproductive organs, lower gastrointestinal
tract, sacral area of spinal cord)
- Most organs have sympathetic and parasympathetic innervation ⇒ have balance for
given organ, how much sympathetic activation are we getting vs parasympathetic,
balance affects how much blood flow or activity we are getting out of particular organ
- Startled response:
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Document Summary

Autonomic nervous system regulates all of internal environment. Sympathetic: fight or flight response, active when you are active, doesn"t activate everything it touches. Parasympathetic: active during rest, doesn"t inhibit everything it touches. Neuronal activity: feeding into smooth muscle, viscera is regulated by smooth muscle. Sympathetic nervous system: mostly out of spinal cord, neurons come down from brain sympathetic preganglionic neurons. Parasympathetic nervous system: nerves out from brainstem directly to organs, except organs of lower viscera (bladder, reproductive organs, lower gastrointestinal tract, sacral area of spinal cord) Most organs have sympathetic and parasympathetic innervation have balance for given organ, how much sympathetic activation are we getting vs parasympathetic, balance affects how much blood flow or activity we are getting out of particular organ. Sympathetic: pupils dilate, increase heart rate, increase force of contraction, could be startled response. Parasympathetic: constrict pupils, slow down heart rate.

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