MEDI7212 Lecture Notes - Lecture 47: Lingual Nerve, Hydrogen Sulfide, Neurological Examination
Document Summary
Smell receptors are a small area of neuroepithelial cells (olfactory mucosa) located along the superior and middle turbinates & upper part of the nasal septum: air travels through superior turbinate (15%), middle turbinate (50%), inferior turbinate (35%) Surface of epithelium is the olfactory mucous layer secreted by submucosal bowman"s glands & goblet cells: pseudostratified columnar cells; over time olfactory epithelium is replaced by respiratory epithelium (reduces smell, cell types. Basal cells: horizontal type (above lamina) & globose (between. Ensheathing cells horizontal/ olfactory neurons: globose are more important. Stem cells; continuous replacement of olfactory receptor neuron every 3-7 weeks: characteristics of both schwann and glial cells. Sustain injury via infection, inflammation and noxious chemical agents: regular turnover of receptor cells via apoptosis (increase caspase3 that activates intrinsic enzymes for cell death) It often resolves, but may persist for several months: head trauma.
