BIOL214 Lecture Notes - Lecture 1: Chemical Polarity, Hydrogen Bond, Organic Compound

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Relate prior knowledge about carbon and water to metabolic biochemistry. Small organic molecule are used to form macromolecules. Water is the most abundant substance in cells (70%) Water as a solvent: good solvent for charged and polar substances, aa and peptides, small alcohols, cho, bad solvent for nonpolar substances, non polar gases, aromatics, alipathic chains. Polar, non polar and alipathic substances: hydrophilic (polar) = water loving, charged, dissolves in water readily, hydrophobic (nonpolar) = water hating, insoluble/dissovles poorly, alipathic = polar and nonpolar regions, see example table. Water as a reactant: can participate readily in chemical reactions, condensation reaction formation of bond between oh + - Oh = gives off water: hydrolysis reaction cleavage of oh + -oh bond by addition of water. Relate prior knowledge about enzymes to metabolic biochemistry. Enzymes are catalysts: enzyme enhances reaction rate by lowering activation energy, enzymes do not affect equilibrium (therefore can be bidirectional)

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