BIOL1007 Lecture Notes - Lecture 5: Enzyme Kinetics, Reaction Rate, Thermodynamics
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Explain the difference between the thermodynamic and kinetic properties of a reaction: thermodynamics is the use of heat to provide energy for different chemical reactions. It is needed to break bonds (requires energy input) before making bonds (releases energy: e. g. Imagine a balloon filled with hydrogen and oxygen gas. If you add a flame to it (energy), the bonds break and rearrange themselves to form new (and more stable) bonds (energy released: reactions: substrate (s) produ(cid:272)t (cid:894)p(cid:895) (cid:449)ill either (cid:271)e: Appreciate how enzymes can be used experimentally (in combination with the labs), and how they combine to form enzymatic pathways that are important for living organisms: ta(cid:271)ilise (cid:862)tra(cid:374)sitio(cid:374)(cid:863) states. E (enzyme) + s (substrate) = es (enzyme-substrate complex) = e*s (enzyme-transition state complex) = e + p (product: enzymes are specific they are relatively big, highly functionalised binding pockets. Describe the similarities and differences between dna and rna polymerases: dna polymerase:
