EXSS2028 Lecture Notes - Lecture 4: Citric Acid Cycle, Computer-Assisted Telephone Interviewing, Phosphoenolpyruvic Acid

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The simplest form of fuel utilisation calculation is the respiratory exchange ratio (rer): vco2 vo2. 6o2 + c6h12o6 6co2 + 6h2o + 38 atp. 23o2 + c16h32o2 16co2 + 16h2o + 129 atp. Massicotte and perronet (absolute values in g/min): Increasing intensity = decreasing reliance on fat & increasing reliance on cho: cross-over point can determine the intensity where 50:50 cho & fat for energy contribution varies on individual basis. Modalities: fed vs. fasted, eating vs. drinking [during, high carb vs. high fat, trained vs. untrained, mode of exercise, morning vs. noon vs. night, males vs. females, rested vs. repeat bouts, continuous vs. incremental. Lactate inhibits glycolysis (high intensity = more lactate pumped into blood) Increase in glucose entering blood supply (from liver) 1990"s (cid:498)in vivo(cid:499) human skeletal muscle (hargreaves and romijn) 40 & 65% vo2max, (cid:1373) carbohydrate oxidation, (cid:1373)glycogenolysis, (cid:1373) pd(, citrate. (cid:1374) acetyl coa, (cid:1374) citrate, (cid:1374) g(cid:888)p, (cid:1374) pd(

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