CAM102 Lecture Notes - Lecture 30: Systemic Lupus Erythematosus, Ankylosing Spondylitis, Rheumatoid Arthritis
Types
Inflammatory
• Arise as a result of a joint inflammation
• Due to (for example)
• Immunological processes
• Crystal-deposition
• Systemic infection
• Examples
• Rheumatoid Arthritis
• Gout
• Reactive arthritis
• Ankylosing spondylitis
• Systemic Lupus Erythematosus (SLE)
Mechanical
• Arise as a result of alteration in the structure of the joint
• Due to (for example)
• Trauma, degeneration, overuse
• Congenital defect
• Previous inflammatory disease
• Example
• Osteoarthritis
• Sports injury
• Other joint trauma
Symptoms (Questions to Ask)
• These will be asked as part of the history of the presenting complaint
Joint Symptoms
• Pain (SOCRATES)
• Stiffness
• Swelling
• Deformity
• Instability, giving way
• Loss of function, weakness
• Crepitus, locking, crackling in joint
• Redness, warmth
• Which joints are involved?
General Symptoms (aka Constitutional Symptoms)
• Fatigue (extreme tiredness)
• Malaise (general feeling of being unwell)
• Sleep disturbance
• Weight loss/anorexia
• Fever/night sweats
• Any other symptoms in any other part of the body
• Rash
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Document Summary
Inflammatory: arise as a result of a joint inflammation, due to (for example) Systemic infection: examples, rheumatoid arthritis, gout, reactive arthritis, ankylosing spondylitis. Mechanical: arise as a result of alteration in the structure of the joint, due to (for example, trauma, degeneration, overuse, congenital defect, previous inflammatory disease, example, osteoarthritis, other joint trauma. Symptoms (questions to ask: these will be asked as part of the history of the presenting complaint. Fatigue (extreme tiredness: malaise (general feeling of being unwell, weight loss/anorexia, any other symptoms in any other part of the body, rash. Family history of osteoarthritis: history of trauma, occupation, age, congenital abnormalities (eg. developmental dysplasia of the hip, women & men affected same. Infectious diseases: viral (hepatitis, hiv, rubella, rrv, bfv, reactive (following gastro-intestinal or sexually transmitted infections, past medical history, eg. Swelling: redness, constitutional symptoms (fever, chills, night sweats etc. ) Neoplastic (tumor in bone around a joint: deep, boring pain.