ANHB1102 Lecture 18: Appetite notes

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ANHB1102: Appetite Notes
White arrow = catabolism
Grey arrow = anabolism
Macronutrients = usable
form of energy
= glucose -> pyruvate/pyruvic acid + 2 ATP
net
NAD+ = derived from ribosome AND a
coenzyme
GLUCOSE -> pyruvic acid -> 1) into krebs
cycle with O2 present
2) lactate without O2 present, when O2
debt present (supply <demand)
Glycolysis, KC, ETC = all produce ATP throughout
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Pyruvic acid -> acetyl CoA
-> continues to TCA cycle
NADH: activated
coenzyme that enters
ETC/OP
- Proteins on IMM
of mitochondria
- ATP synthase (last
protein) to power through
producing ATP
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Document Summary

= glucose -> pyruvate/pyruvic acid + 2 atp net. Nad+ = derived from ribosome and a coenzyme. Glucose -> pyruvic acid -> 1) into krebs cycle with o2 present: lactate without o2 present, when o2 debt present (supply atp e- + o2 = h2o. Ghrelin, adrenalin = tells us when we are. 3 hungry: body temperature = cold stimulates appetite because need to burn more macronutrient to keep warm and provide atp. Satiety centre: when lesion present, has undestructed appetite. Feed centre: when lesion present, stimulate thoughts of eating thus when destroyed = no appetite. Npy = feed directly into system for anger. Neuropeptides = peptides formed within hypothalamus, send signals to higher levels of hypothalamus into cortex to tell if hungry or not. Stimulants = tell us when we are hungry.

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