PSYC-375 Lecture Notes - Lecture 4: Anabolic Steroid, Gaba Receptor, Veterinary Medicine
11 Mar 2019
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Module 4: enhancers, depressants, and drugs as medicine and how they alter brain. First things first: anabolic steroids are also known as anabolic-androgenic steroids. Drug manufacturers will try to maximize the anabolic activity and minimize the androgenic activity of a drug that would benefit athletes; however, a purely anabolic drug does not exist. Androgen receptors are present in many places in the body, including skeletal muscles. The receptor itself is located in the cytoplasm of the cell, and when an agonist (testosterone or steroid) binds to it, the complex moves into the nucleus. In the nucleus, the complex binds to dna and regulates gene expression. In muscle cells, this results in an increase in protein production. Barbiturates and their mechanism of action: barbiturates (barbs) are depressants that were first synthesized from barbituric acid and marketed in the early 1900s, they were popular for treating a number of conditions. Nowadays, benzodiazepines taken over their role, although barbs are sometimes still prescribed.
