BIOL 1090 Lecture Notes - Lecture 12: Chromosome Abnormality, Acridine Orange, Hydroxylamine

• School: University of Guelph
• Department: Biology
• Course: BIOL 1090
• Professor: Dennis Baker

Document Summary

A tautomeric shift: its a rare shift, movement of h atoms from one position in a purine or pyrimidine to another. Mispairs resulting from the change of one tautomer into another, termed a tautomeric shift. When the bases are in their rare enol or imino states, they can form rare a-c and g-t base pairs. A transition replaces a pyrimidine with another pyrimidine or a purine for another purine. (same with the same) A transversion replaces a pyrimidine with a purine of a purine with a pyrimidine. (purine with pyrim. dif-dif) 12 different base pair substitutions in dna. Insertions or deletions on one or two base pairs that alters the reading frame of the gene distal to the site of the mutation. Protein sequence changes dramatically after the frameshift. Transposable elements or viruses can disrupt functioning genes by insertion. What can you say following this picture? what does it remind you of? mosquitoes: mutagenesis.