BIOL 1090 Lecture Notes - Lecture 9: Formylation, Ribosomal Rna, Aminoacyl Trna Synthetase

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Covalently attached to the amino group of the next amino acid. Determined by the spatial organization of amino acids. Determined by the over all folding of the complete polypeptide. In some proteins, more than one polypeptide interacts to make a functional protein. Made in the nucleus and translated into protein by many ribosomes in the cytoplasm. Ribosomes are made up if polypeptides and rna molecules. Soluble proteins involved in polypeptide chain initiation$, elongation, and termination. The nucleolus site of eukaryotic rrna synthesis and ribosome assembly. Adapters between amino acids and the codons in mrna. Anticodon of the trna base pairs with the codon of mrna. The amino acid is covalently attached to the 3" end of the trna trna often contain modified nucleotides. Cell contain at least one trna synthetase for each amino acid. Amino group of the methionine on the initiator trna is nor formylated.

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