ANBI 360.3 Lecture Notes - Lecture 9: Scottish Fold, Achondroplasia, Polydactyly
20 Jun 2018
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LECTURE 9
!
Genetic Variation in cats!
less than in dogs!•
registries often by phenotype (not by pedigree)!•
!
head shape!•
ear shape!•
table length!•
coat type!•
coat color!•
!
in the last few years there is much more variation in cats!
!
Head shape!
compressed!•
Persian cat!◦
Ear shape!
tufted!•
very old type of mutation!◦
main coon cat!◦
folded!•
do not perk up!◦
curled!•
!
Scottish fold!
apex of the ears is bent forward because of a defect in cartilage development!•
cartilage defects occur throughout the body!•
homozygote may have crippling overgrowth of cartilage!•
!
Tail Length!
manx!•
short tail!◦
stumpy (missing only a few vertebras)!‣
rumby ( very short)!‣
homozygous for this trait dies in utero!◦
long tail is normal!•
!
Polydactyly!
1-4 feet!•
6 or 7 digits!•
may not be the same on very paw!•
!
dwarfism!
shortened limbs!•
example: munchkin!•
achondroplastic dwarfism!◦
shorted legged condition!◦
gene is dominant and homozygous lethal!◦
normal body and head size!•
Document Summary
Genetic variation in cats less than in dogs registries often by phenotype (not by pedigree) head shape ear shape table length coat type coat color in the last few years there is much more variation in cats. Ear shape tufted very old type of mutation main coon cat folded do not perk up curled. Scottish fold apex of the ears is bent forward because of a defect in cartilage development cartilage defects occur throughout the body homozygote may have crippling overgrowth of cartilage. Tail length manx short tail stumpy (missing only a few vertebras) rumby ( very short) homozygous for this trait dies in utero long tail is normal. Two melanin pigments melanocyte color classes: agouti, msh. Melanocortin receptor 1 gene four alleles that are identi ed at mc1r. E^m allele of mc1r melanistic mask afghan hound. K^b allele negates expression of phaeomelanin ( red) pigment from a^y or a^t or a^w.
