HLTH355 Lecture Notes - Lecture 69: Baud, International Agency For Research On Cancer, Breast Cancer
27 Nov 2018
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Slide 20:
Alcohol and Hospitalizations in Canada (2015-2016)
• CTV article titled “more Canadians hospitalized for alcohol than heart attacks last year: study”
• 77,000 – hospitalizations entirely caused by alcohol
• 75,000 – heart attacks
• CIHI. Alcohol Harm in Canada (2017). https://www.cihi.ca/sites/default/files/document/report-
alcohol-hospitalizations-en-web.pdf
Slide 21:
Alcohol Causes 7 types of Cancer
The relationship between increasing amount of average daily alcohol consumption and the relative risk
for cancer (GBD 2016. Lancet, 2018)
1. Mouth and Oropharynx Cancers
2. Esophageal Cancer
3. Larynx Cancer
4. Colon Cancer
5. Rectal Cancer
6. Liver Cancer
7. Breast cancer (women only)
• According to the WHO’s IARC, on the basis of the sum total of evidence of studies of cancer in
humans and animal models, as well as mechanistic studies, alcoholic beverages are carcinogenic
to humans and are causally related to malignant tumours in 7 sites, including mouth, esophageal,
larynx, colon, rectal, liver, and female breast. Similar conclusions about the causal relationship
between alcohol and cancer were also reached by other expert groups from the WCRF and the
American Society for Clinical Oncology. In 2012, alcohol is estimated to have caused
approximately half a million deaths from cancer; 5.8% of cancer deaths world-wide.
• For all these there is a dose-response relationship, where the increase in cancer risk with
increased average consumption is monotonic. There does not appear to be any variation by
beverage type.
Sources: International Agency for Research on Cancer (IARC). International Agency for Research on
Cancer Monographs on the Evaluation of Carcinogenic Risks to Humans. Volume 96, 2008.
Global Burden of Disease Study 2016. Alcohol use and burden for 195 countries and territories, 1990-
2016: a systematic analysis for the GBD Study 2016. Lancet, Online first.
DOI: https://doi.org/10.1016/S0140-6736(18)31310-2.
Bagnardi et al. Alcohol consumption and site-specific cancer risk: a comprehensive dose–response meta-
analysis. Br J Cancer 2015; 112: 580–93.
Slide 22:
Document Summary
Alcohol and hospitalizations in canada (2015-2016: ctv article titled more canadians hospitalized for alcohol than heart attacks last year: study , 77,000 hospitalizations entirely caused by alcohol, 75,000 heart attacks, cihi. The relationship between increasing amount of average daily alcohol consumption and the relative risk for cancer (gbd 2016. Similar conclusions about the causal relationship between alcohol and cancer were also reached by other expert groups from the wcrf and the. There does not appear to be any variation by beverage type. Sources: international agency for research on cancer (iarc). Cancer monographs on the evaluation of carcinogenic risks to humans. Alcohol use and burden for 195 countries and territories, 1990- 2016: a systematic analysis for the gbd study 2016. Alcohol consumption and site-specific cancer risk: a comprehensive dose response meta- analysis. Alcohol linked to several major cancers by american society of clinical oncology. Cancers attributed to alcohol: 5. 5% of all new cancers, 5. 8% of all cancer deaths.
