PSYC 207 Lecture Notes - Lecture 15: Axon Terminal, Methylphenidate, Free Base
Document Summary
Commonly used for medicinal purposes and commonly abused (cocaine, Used as decongestant, weight loss, increased energy. D-amphetamine: breaking down of isomers = l and d isomers. Useful for congestion, narcolepsy, weight loss, adhd, performance enhancement . Very high addiction potential and high dopamine release. Stimulant psychosis: people who take a lot of psychostimulants. Methylphenidate demonstrate very similar positive symptoms of those of schizophrenia. Khat is relatively benign but treated like menace. Derived from coca plant; used for ages. He was high on cocaine when he formulated many psychological ideas. Polydrug use: mixing substances which produces new drugs/compounds (eg, alcohol + cocaine = cocaethylene) Cocaine blocks dat and reuptake, causing prolonged effect in synapse, now enzymes have to work harder. Encourages more da to be stored in vesicles. At high doses, blocks sodium channels = used as an anesthetic because of the blocking of sodium, it blocks ap and epsps. Causes transporter to spit da into the axon.
