PSYC 207 Lecture Notes - Lecture 16: Anticonvulsant, Stimulant, Prefrontal Cortex
Document Summary
Psychostimulants travel from vta to nucleus accumbens. Dat, net and sert mechanisms are very similar. Each system can transport the other but are most sensitive to their own neurotransmission. In rats, called stereotypy: compulsively grooming or chewing on bars. In humans, called punding: species specific behaviours, grinding teeth and picking at skin. A) give saline, only one lever comes out. B) give drug, a second lever comes out. Once they are trained to press lever 1 when they feel no effects, and lever 2 when they feel the high. C) give a third drug like cocaine, they still press lever 2 bc they cant tell which type of drug it is. Similar to positive full blown symptoms of schizophrenia. High doses: cocaine is a na+ channel blocker, na+ is important for ap so you risk silencing your neuron communication. Poor dental hygiene due to poor living condition s. More pronounced for reinforcing effect of drug.
