HLSC 2110U Lecture Notes - Lecture 8: Acetyl-Coa, Citric Acid Cycle, Pantothenic Acid
2 Feb 2019
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Document Summary
Tca cycle, krebs cycle, citric acid cycle (cac) Plays several roles in metabolism since it is the final pathway where oxidative metabolism of carbs, amino acids, and fatty acids converge. Their carbon skeletons are converted to carbon dioxide. Oxidation pathway provides energy for the production of the majority of atp in most animals. Cycle occurs in the mitochondria so it is in close proximity to the reactions of the electron transport (which oxidize the reduced coenzymes produced by the cycle) Most of body"s catabolic pathways converge on the tca cycle. Participates in a number of important synthetic reactions: Formation of glucose from carbon skeletons of some amino acids. Provides building blocks for synthesis of some amino acids and heme. This cycle should not be viewed as a closed circle but as a traffic circle with compounds entering and leaving as required, making it a central pathway of energy metabolism.
