HLSC 2110U Lecture Notes - Lecture 16: Hyperplasia, Pear-Shaped, Adiponectin
13 Mar 2019
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Document Summary
Anatomical differences in fat deposition: upper body obesity. Upper body obesity is abdominal fat not favourable because usually the liver takes up the fats and lipids immediately. Pear shaped body shapes is mostly found with women and is less harmful. 1 hypertrophic and hyperplastic changes thought to occur in severe obesity. Fat droplets increase in number & size. This is important because when we lose weight, the number of fat cells do not decrease. Therefore, that is why it is important to maintain weight loss after losing a significant amount of weight. Polygene a trait that is controlled by more than one gene. Japanese and chinese populations usually have a low bmi. When they migrate to the us, the environment has changed for these people and their bmis increase. Injection of leptin caused overweight mice to lose weight. Hormone of adipose tissue (along with adiponectin and resistin) Secretion of leptin well fed state.
