BIO 3422 Lecture Notes - Lecture 2: Lipophilicity, Transmembrane Protein, Membrane Protein

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8 Mar 2018
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~60% body weight made up of fluid total body water (tbw) Fluid within the confines of the cell membrane. The body has 37 trillion cells all with icf that make up 2/3rd of tbw: extracellular fluid (efc) Fluid outside the confines of the cell membrane which is subdivided. Interstitial fluid (isf: fluid found in the interstices, the space outside of and in between cells, plasma, fluid within blood vessels/fluid part of the blood. Phospholipid bilayer is organized to form cell membrane and determine what makes it into and. * relative size: lipid size >>> phosphate size* Phosphate = hydrophilic and polar, charged molecules. Like attracts like: lipid attracts to lipid: phosphate attracts to water. Note: cell membrane is composed primarily of lipophilic substance cell membrane is viewed as a lipophilic structure. Providing mechanical strength that prevents separation of cells and resist force localized junction does(cid:374)(cid:859)t block passage way molecules travel around desmosomes: gap junction.

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