BIOL 031 Lecture Notes - Lecture 30: Conformational Change, Cell Surface Receptor, The Membranes
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13 Aug 2020
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Simple diffusion across a membrane: the rate of movement through a membrane is faster if, the membranes surface area is larger, the membrane is thinner, the concentration gradient is larger, the membrane is more permeable than the molecule. Membrane permeability to a molecule depends on: the molecules lipid solubility, the molecule"s size, the lipid composition of the membrane. Lipophilic molecules move by simple diffusion across lipids. The rate of diffusion is related to surface area, concentration gradient, and membrane permeability. Open channels: all things to move in or out. Gated channels: chemically gated channels, voltage-gated channels: change in the membrane potential is required for them to open, mechanically gated channels: a mechanical reaction (temp. ) allows them to open. Number of molecules transported: uniport carriers: carry 1 thing in and out, symport carriers: carry 2 things in the same direction, antiport carriers: carry 2 things in the opposite direction. Saturation: dependent on the number of carrier molecules: transport maximum.
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