ASTRO-110 Lecture Notes - Lecture 23: Sensory System, Lateral Sulcus, Olfactory Bulb

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Chemotopic map topographic organization of the olfactory bulbs. New olfactory receptor cells are created throughout each individual"s life to replace those that have deteriorated. Once created, the new axons which grow until they reach appropriate target sites in the olfactory bulb. Each new cell only survives a few weeks before being replaced. Each bulb projects axons to several structures of the medial temporal lobes, including the amygdala and the piriform cortex. Piriform cortex an area of medial temporal cortex adjacent to the amygdala. Piriform cortex is considered to be primary olfactory cortex. Olfactory system is only sensory system whose major sensory pathway reaches the cerebral cortex without first passing through thalamus. Two major olfactory pathways leave the amygdala-piriform area. Limbic pathway thought to mediate emotional response to odors. Other projects via medial dorsal nuclei of the thalamus to the orbitofrontal cortex. Thalamic-orbitofrontal pathway thought to mediate the conscious perception of odors.

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