BIOLOGY 3 Lecture Notes - Lecture 28: Alpha Cell, Beta Cell, Diabetic Neuropathy

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24 Dec 2020
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A homeostatic control system has three functional components. The signals in the system are a) blood sugar levels, b) hormones, either gluagon or insulin. Maintenance of blood sugar levels is mostly dependent on hormonal signals. Glucagon is a hormone peptide of 29 amino acids. Insulin is a bit more complex, made up of one 21 amino acid peptide and a second peptide of 30 amino acids that are joined together via disulphide bonds. The cells of the pancreas function as both the receptor and the control center. Alpha cells sense when blood sugar levels have dropped too low and release glucogon. Beta cells sense when blood sugar levels are too high and release insulin. Blood sugar (glucose) needs to be kept between about 3. 8 and 5. 8 millimoles per litre - that"s about 1 teaspoon (5 grams) dissolved in the 5 litres (the average persons blood volume). "hypo" - hypoglycemia - the prefix hypo meaning below normal).

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