PHYSIOL 1 Lecture Notes - Lecture 1: Myocyte, Skeletal Muscle, Immunoglobulin Light Chain
Document Summary
Deep folds of sarcolemma into muscle fiber. Help to get ap to myofibrils that run through skeletal muscle fiber deep within the cell. Like the cytoplasm-enzymes, lipid blobs, glycogen, mitochondria embedded. Specialized type of er in the muscle fibers. Terminal cisternae: sacs of ca2+ that interact with t-tubule. 100"s-1000"s of myofibrils in ever muscle fiber. Specific organization of proteins (give cell a striated appearance) Form a long, rigid, insoluble tail: provides structure. Came from light chains that attach to the heavy chains. Lots of myosin molecules come together to form thick filaments. Cross-bridges radiate out from the body; staggered along the length of thick filament. Thin filaments only; z line runs through it. Region of sarcomere where thin and thick filaments don"t overlap. Wrapped around actin covering the binding sites for myosin (when muscle is relaxed) Protein that anchors thin filaments- also connects adjacent myofibrils.
