BIOL 141 Lecture Notes - Lecture 27: Pyruvic Acid, Cyanide Poisoning, Glyceraldehyde 3-Phosphate

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Transmembrane in the inner membrane of the mitochondria. Complexes couple the active transport of h+ across membrane with redox reactions. If the protons are moving in one direction via active transport . The side without the h+ is the matrix. The side with the h+ is the intermembrane space. When active, we get a high concentration of protons, low ph. Pmf is also used by another transmembrane protein, atp synthase that carries out oxidative phosphorylation and synthesizes atp. Movement of protons back into matrix is passive movement. Active transport: transferring potential energy stored in covalent molecules to the form of a concentration gradient. Requires energy source, such as atp or an ion pump. Pe in atp is transferred into the form of the concentration gradient that can be used to do work. Can drive passive transport or pmf with atp synthase. High pe substrate converted to a low pe product.

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