BIOL 120 Lecture Notes - Lecture 5: Cellular Respiration, Autoregulation, Cell Membrane
Document Summary
Hormones are dropped into the blood and sent to effectors. Local communication, nothing is going into the cleft, nothing is going into the blood, within same tissue. Neurotransmitters can come back and bind into their own membrane. Needs something to transport it around the blood. Endocrine hormone is released into the blood stream, picked up by neighboring capillaries. Circulating hormones are short lived, hydrophilic is short lived because they don"t need a binding protein, they don"t need one because they dissolve well in plasma. How long does it take for half of the substance to disappear from. Hydrophilic hormones can blow right through the plasma membrane. Carrier protein is sent in and nuclear receptors are sent in to receive ligand that has transcription factor, once bound causes transcription. Binding affinity is stronger for a receptor. Low receptor density, causes for a weak response.
