CO SCI 136 Lecture Notes - Lecture 19: Clinical Trial, Random Effects Model, Occupational Safety And Health
Document Summary
Numerous studies have reported that brief interventions delivered in primary care are effective in reducing excessive drinking. However, much of this work has been criticised for being clinically unrepresentative. This review aimed to assess the effectiveness of brief interventions in primary care and determine if outcomes differ between efficacy and effectiveness trials. A pre-specified search strategy was used to search all relevant electronic databases up to. 2006. we also hand-searched the reference lists of key articles and reviews. we included randomised controlled trials (rct) involving patients in primary care who were not seeking alcohol treatment and who received brief intervention. Two authors independently abstracted data and assessed trial quality. Random effects meta- analyses, subgroup and sensitivity analyses and meta-regression were conducted. Brief interventions can reduce alcohol consumption in men, with benefit at a year after intervention, but they are unproven in women for whom there is insufficient research data. Longer counselling has little additional effect over brief intervention.
