BIOL 1201 Lecture : Monday Lect Notes 10 8

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15 Mar 2019
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Replication dna polymerase :molecule that is going to make dna. Last step fuse sections dna ligase : ties the backbones together. Builds 5" to 3" prime and anti parallel. Hand out backbones new piece is always 5" to 3" anti-parallel. Lagging stings are produced in segments, replicating the opposite of the opening side of the replication bubble. They will either be too narrow or too far apart, it will not fit right. Each nucleotide brings its own energy-in a triphosphate form: strands separate and unwind: (helicase, topoisomerases, and ssb proteins. 2. add primer (primase: replication (dna polymerase, fuse sections/fragments( dna ligase) new sections built 5"-3" and anti-parallel. Why does dna polymerase only build 5" to 3"? its the only way it can proofread and still bring the energy-because of where the energy comes from. It depends on the damage-if a single nucleotide get knocked out you can replace it.

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