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Lecture 8

GN 301 Lecture Notes - Lecture 8: Fibroblast Growth Factor Receptor 3, Epistasis, Punnett Square

Course Code
GN 301
Marian- Elizabeth B.Gardner

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2.3 Inheritance and Pedigrees
Thursday, September 21, 2017
10:51 AM
Remember these: gene, allele, locus, phenotype, genotype, homozygous, heterozygous
Remember: Albinism
Proband is the person who asked for the pedigree to be made
Autosomal Genes: two shaded people make unshaded child= dominant; two unshaded people
make shaded child= recessive
If e ko soeoe’s pheotype, if asked hat peretage they ill e heterozygous, you are
only looking at the Punnet square squares that show that phenotype (ex: 2/3 not 2/4)
Law of Random Segregation
o Heterozygous people make two gamete types equally frequently
o Each gamete has equal chance of getting either allele (50%)
Ex: Ff, both F and f have equal chance of being passed down
Law of Independent Assortment
o Migration of alleles into gametes does not affect allele migration at second gene
Ex: FfTt individuals Ff does not affect Tt allele migration
o Equal frequency of the 4 gametes produced
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