01:119:115 Lecture Notes - Lecture 5: Thermodynamics, Homeostasis, Exergonic Reaction

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Cell respiration: anabolic pathways, build complex molecule from simpler ones, use energy, ex. Synthesis of protein from amino acids: free-energy change in chemical reactions, energy= capacity to cause change/do work, kinetic energy, = e of motion, potential energy, = stored e has not yet been used. Total e available to do work decreases over time. Gibbs free energy (g)- the e available to do work +: more energy, -: energy came out. But: glucose + oxygen carbon dioxide + water + energy : can see how g changes during rx. G < 0 = energy is released from a reaction. Glucose + oxygen carbon dioxide + water + atp. G > 0 = energy is added to cause reactions, non-spontaneous. Cells use atp to carry energy: atp (adenosine triphosphate, spring loaded and high energy, 3 phosphate groups. Coupled reactions: pair exergonic reaction (provides e) with, endergonic reaction (requires e) Atp drives endergonic reactions by phosphorylation: passing up a phosphate group.

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